功能: function:Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.,similarity:Contains 1 Link domain.,similarity:Contains 16 EGF-like domains.,similarity:Contains 2 laminin EGF-like domains.,similarity:Contains 7 FAS1 domains.,subunit:Interacts with CHID1.,tissue specificity:High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Membrane ; Single-pass type I membrane protein .
组织表达: High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells.
科研货号: PLA007991
STAB1 Polyclonal Antibody
Catalog NoPLA007991
Product information
基因名称: STAB1 FEEL1 KIAA0246
蛋白名称: Stabilin-1 (Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1) (FEEL-1) (MS-1 antigen)
功能: function:Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.,similarity:Contains 1 Link domain.,similarity:Contains 16 EGF-like domains.,similarity:Contains 2 laminin EGF-like domains.,similarity:Contains 7 FAS1 domains.,subunit:Interacts with CHID1.,tissue specificity:High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Membrane ; Single-pass type I membrane protein .
组织表达: High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells.