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MMEL1 Polyclonal Antibody
商品货号: PLA007964
适 应 性: 人,大鼠,小鼠
WB ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: MMEL1 MELL1 MMEL2 NEP2
  • 蛋白名称: Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]
  • Human_gene_id: 79258
  • Human_swiss_prot_no: Q495T6
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/Q495T6/entry
  • Mouse_swiss_prot_no: Q9JLI3
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9JLI3
  • Rat_swiss_prot_no: P0C1T0
  • Rat_swiss_link: http://www.uniprot.org/uniprot/O54941P0C1T0
  • 特异性: MMEL1 Polyclonal Antibody detects endogenous levels of protein.
  • 组成: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000 ELISA 1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 实测条带: 85kD
  • 功能: catalytic activity:Preferential cleavage of polypeptides between hydrophobic residues, particularly with Phe or Tyr at P1'.,cofactor:Binds 1 zinc ion per subunit.,enzyme regulation:Inhibited by thiorphan and phosphoramidon.,function:Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificiy with MME and cleaves peptides at the same amide bond.,PTM:N-glycosylated.,similarity:Belongs to the peptidase M13 family.,subcellular location:A secreted form produced by proteollytic cleavage also exists.,tissue specificity:Predominantly expressed in testis. Weakly expressed in brain, kidney and heart.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Membrane; Single-pass type II membrane protein. Secreted. A secreted form produced by proteolytic cleavage also exists. .
  • 组织表达: Predominantly expressed in testis. Weakly expressed in brain, kidney and heart.
  • 科研货号: PLA007964
MMEL1 Polyclonal Antibody
Catalog No PLA007964
Product information
  • 基因名称: MMEL1 MELL1 MMEL2 NEP2
  • 蛋白名称: Membrane metallo-endopeptidase-like 1 (EC 3.4.24.11) (Membrane metallo-endopeptidase-like 2) (NEP2(m)) (Neprilysin II) (NEPII) (Neprilysin-2) (NEP2) (NL2) [Cleaved into: Membrane metallo-endopeptidase-like 1, soluble form (Neprilysin-2 secreted) (NEP2(s))]
  • Human_gene_id: 79258
  • Human_swiss_prot_no: Q495T6
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/Q495T6/entry
  • Mouse_swiss_prot_no: Q9JLI3
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9JLI3
  • Rat_swiss_prot_no: P0C1T0
  • Rat_swiss_link: http://www.uniprot.org/uniprot/O54941P0C1T0
  • 特异性: MMEL1 Polyclonal Antibody detects endogenous levels of protein.
  • 组成: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000 ELISA 1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 实测条带: 85kD
  • 功能: catalytic activity:Preferential cleavage of polypeptides between hydrophobic residues, particularly with Phe or Tyr at P1'.,cofactor:Binds 1 zinc ion per subunit.,enzyme regulation:Inhibited by thiorphan and phosphoramidon.,function:Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificiy with MME and cleaves peptides at the same amide bond.,PTM:N-glycosylated.,similarity:Belongs to the peptidase M13 family.,subcellular location:A secreted form produced by proteollytic cleavage also exists.,tissue specificity:Predominantly expressed in testis. Weakly expressed in brain, kidney and heart.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Membrane; Single-pass type II membrane protein. Secreted. A secreted form produced by proteolytic cleavage also exists. .
  • 组织表达: Predominantly expressed in testis. Weakly expressed in brain, kidney and heart.
  • 科研货号: PLA007964
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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