FKB1B Polyclonal Antibody

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商品货号： PLA007893

适应性： 人,大鼠,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： FKBP1B FKBP12.6 FKBP1L FKBP9 OTK4
蛋白名称： Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12)
Human_gene_id： 2281
Human_swiss_prot_no： P68106
Human_swiss_link： https://www.uniprot.org/uniprotkb/P68106/entry
Mouse_swiss_prot_no： Q9Z2I2
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z2I2
Rat_swiss_prot_no： P97534
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P97534
特异性： FKB1B Polyclonal Antibody detects endogenous levels of protein.
组成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
实测条带： 11kD
功能： catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by both FK506 and rapamycin.,function:Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the FKBP-type PPIase family. FKBP1 subfamily.,similarity:Contains 1 PPIase FKBP-type domain.,tissue specificity:Ubiquitous for both isoforms with highest levels in brain and thymus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Sarcoplasmic reticulum .
组织表达： Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus.
科研货号： PLA007893

FKB1B Polyclonal Antibody

Catalog No PLA007893

Product information

基因名称： FKBP1B FKBP12.6 FKBP1L FKBP9 OTK4
蛋白名称： Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12)
Human_gene_id： 2281
Human_swiss_prot_no： P68106
Human_swiss_link： https://www.uniprot.org/uniprotkb/P68106/entry
Mouse_swiss_prot_no： Q9Z2I2
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9Z2I2
Rat_swiss_prot_no： P97534
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P97534
特异性： FKB1B Polyclonal Antibody detects endogenous levels of protein.
组成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
实测条带： 11kD
功能： catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited by both FK506 and rapamycin.,function:Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.,similarity:Belongs to the FKBP-type PPIase family. FKBP1 subfamily.,similarity:Contains 1 PPIase FKBP-type domain.,tissue specificity:Ubiquitous for both isoforms with highest levels in brain and thymus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Sarcoplasmic reticulum .
组织表达： Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus.
科研货号： PLA007893

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