功能: catalytic activity:Cleavage of the 143-Ser-|-Lys-144 bond in insulin-like growth factor binding protein (IGFBP)-5.,cofactor:Binds 1 zinc ion per subunit.,function:Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3.,similarity:Belongs to the peptidase M43B family.,similarity:Contains 5 Sushi (CCP/SCR) domains.,subunit:Monomer.,tissue specificity:Expressed abundantly in placenta, and non-pregnant mammary gland with low expression in the kidney, fetal brain and pancreas.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted .
组织表达: Expressed abundantly in placenta, and non-pregnant mammary gland with low expression in the kidney, fetal brain and pancreas.
科研货号: PLA007883
PAPP2 Polyclonal Antibody
Catalog NoPLA007883
Product information
基因名称: PAPPA2 PLAC3
蛋白名称: Pappalysin-2 (EC 3.4.24.-) (Pregnancy-associated plasma protein A2) (PAPP-A2) (Pregnancy-associated plasma protein E1) (PAPP-E)
功能: catalytic activity:Cleavage of the 143-Ser-|-Lys-144 bond in insulin-like growth factor binding protein (IGFBP)-5.,cofactor:Binds 1 zinc ion per subunit.,function:Metalloproteinase which specifically cleaves IGFBP-5. Shows limited proteolysis toward IGFBP-3.,similarity:Belongs to the peptidase M43B family.,similarity:Contains 5 Sushi (CCP/SCR) domains.,subunit:Monomer.,tissue specificity:Expressed abundantly in placenta, and non-pregnant mammary gland with low expression in the kidney, fetal brain and pancreas.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted .
组织表达: Expressed abundantly in placenta, and non-pregnant mammary gland with low expression in the kidney, fetal brain and pancreas.