功能： catalytic activity:An acylcholine + H(2)O = choline + a carboxylate.,disease:Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) [MIM:177400]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait.,miscellaneous:Cholinesterase is highly reactive with organophosphate esters.,similarity:Belongs to the type-B carboxylesterase/lipase family.,subunit:Homotetramer. The tetramer is composed of two dimers. The two subunits in a dimer are linked by a disulfide bond.,tissue specificity:Present in most cells except erythrocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted .
组织表达： Detected in blood plasma (at protein level). Present in most cells except erythrocytes.
功能： catalytic activity:An acylcholine + H(2)O = choline + a carboxylate.,disease:Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) [MIM:177400]. BChE deficiency is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine or mivacurium and other ester local anesthetics. The duration of the prolonged apnoea varies significantly depending on the extent of the enzyme deficiency. BChE deficiency is a multifactorial disorder. The hereditary condition is transmitted as an autosomal recessive trait.,miscellaneous:Cholinesterase is highly reactive with organophosphate esters.,similarity:Belongs to the type-B carboxylesterase/lipase family.,subunit:Homotetramer. The tetramer is composed of two dimers. The two subunits in a dimer are linked by a disulfide bond.,tissue specificity:Present in most cells except erythrocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted .
组织表达： Detected in blood plasma (at protein level). Present in most cells except erythrocytes.
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