SIGIR Polyclonal Antibody

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商品货号： PLA007762

适应性： 人,大鼠,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： SIGIRR UNQ301/PRO342
蛋白名称： Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8)
Human_gene_id： 59307
Human_swiss_prot_no： Q6IA17
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q6IA17/entry
Mouse_swiss_prot_no： Q9JLZ8
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9JLZ8
Rat_swiss_prot_no： Q4V892
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941Q4V892
特异性： SIGIR Polyclonal Antibody detects endogenous levels of protein.
组成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
实测条带： 45kD
功能： function:Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 TIR domain.,subunit:Interacts with IL1R1, IRAK1, TLR4, TLR5, TLR9 and TRAF6. Upon IL-1 stimulation found in a complex at least composed of IL1R1, SIGIRR, MYD88, IRAK1 and TRAF6. Upon stimulation with LPC found in a complex at least composed of TLR4, SIG1IR, MYD88, IRAK1 and TRAF6.,tissue specificity:Mainly expressed in epithelial tissues such as kidney, lung and gut.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane ; Single-pass type III membrane protein .
组织表达： Mainly expressed in epithelial tissues such as kidney, lung and gut.
科研货号： PLA007762

SIGIR Polyclonal Antibody

Catalog No PLA007762

Product information

基因名称： SIGIRR UNQ301/PRO342
蛋白名称： Single Ig IL-1-related receptor (Single Ig IL-1R-related molecule) (Single immunoglobulin domain-containing IL1R-related protein) (Toll/interleukin-1 receptor 8) (TIR8)
Human_gene_id： 59307
Human_swiss_prot_no： Q6IA17
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q6IA17/entry
Mouse_swiss_prot_no： Q9JLZ8
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9JLZ8
Rat_swiss_prot_no： Q4V892
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941Q4V892
特异性： SIGIR Polyclonal Antibody detects endogenous levels of protein.
组成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
实测条带： 45kD
功能： function:Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 TIR domain.,subunit:Interacts with IL1R1, IRAK1, TLR4, TLR5, TLR9 and TRAF6. Upon IL-1 stimulation found in a complex at least composed of IL1R1, SIGIRR, MYD88, IRAK1 and TRAF6. Upon stimulation with LPC found in a complex at least composed of TLR4, SIG1IR, MYD88, IRAK1 and TRAF6.,tissue specificity:Mainly expressed in epithelial tissues such as kidney, lung and gut.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane ; Single-pass type III membrane protein .
组织表达： Mainly expressed in epithelial tissues such as kidney, lung and gut.
科研货号： PLA007762

Hunan UPT Biotechnology Co.,Ltd

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