功能： function:Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.,similarity:Belongs to the adaptor complexes large subunit family.,similarity:Contains 1 GAE domain.,subcellular location:Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.,subunit:Adaptor protein complex 1 (AP-1) is an heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta-type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or AP1S2 or AP1S3). Binds RABEP1 and AP1GBP1.,tissue specificity:Widely expressed.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Golgi apparatus . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm . Cytoplasm, perinuclear region . Cytoplasmic vesicle, clathrin-coated vesicle . Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex (PubMed:12773381). Co-localizes with AFTPH/aftiphilin in the cytoplasm (PubMed:15758025). .
组织表达： Widely expressed.
科研货号： PLA007756
AP1G1 Polyclonal Antibody
Catalog NoPLA007756
Product information
基因名称： AP1G1 ADTG CLAPG1
蛋白名称： AP-1 complex subunit gamma-1 (Adapter-related protein complex 1 subunit gamma-1) (Adaptor protein complex AP-1 subunit gamma-1) (Clathrin assembly protein complex 1 gamma-1 large chain) (Gamma1-adaptin) (Golgi adaptor HA1/AP1 adaptin subunit gamma-1)
功能： function:Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.,similarity:Belongs to the adaptor complexes large subunit family.,similarity:Contains 1 GAE domain.,subcellular location:Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.,subunit:Adaptor protein complex 1 (AP-1) is an heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta-type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or AP1S2 or AP1S3). Binds RABEP1 and AP1GBP1.,tissue specificity:Widely expressed.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Golgi apparatus . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm . Cytoplasm, perinuclear region . Cytoplasmic vesicle, clathrin-coated vesicle . Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex (PubMed:12773381). Co-localizes with AFTPH/aftiphilin in the cytoplasm (PubMed:15758025). .
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