功能: domain:Contains FG repeats. The FG repeat region is required for acting as a cofactor of HIV-1 Rev.,function:Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.,PTM:O-glycosylated.,similarity:Contains 1 Arf-GAP domain.,subunit:Interacts with EPS15R and EPS15.,tissue specificity:Ubiquitously expressed.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus . Cytoplasmic vesicle .
组织表达: Ubiquitously expressed.
科研货号: PLA007691
AGFG1 Polyclonal Antibody
Catalog NoPLA007691
Product information
基因名称: AGFG1 HRB RAB RIP
蛋白名称: Arf-GAP domain and FG repeat-containing protein 1 (HIV-1 Rev-binding protein) (Nucleoporin-like protein RIP) (Rev-interacting protein) (Rev/Rex activation domain-binding protein)
功能: domain:Contains FG repeats. The FG repeat region is required for acting as a cofactor of HIV-1 Rev.,function:Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.,PTM:O-glycosylated.,similarity:Contains 1 Arf-GAP domain.,subunit:Interacts with EPS15R and EPS15.,tissue specificity:Ubiquitously expressed.,