功能： domain:The C-terminal domain is necessary for protein interactions.,function:Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.,similarity:Belongs to the DNA polymerase type-Y family.,similarity:Contains 1 BRCT domain.,similarity:Contains 1 umuC domain.,subunit:Monomer. Binds MAD2L2, POLH, POLI, POLK and REV3L. May bind ITGA3.,tissue specificity:Ubiquitous.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus .
组织表达： Ubiquitous.
科研货号： PLA007652
REV1 Polyclonal Antibody
Catalog NoPLA007652
Product information
基因名称： REV1 REV1L
蛋白名称： DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase)
功能： domain:The C-terminal domain is necessary for protein interactions.,function:Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.,similarity:Belongs to the DNA polymerase type-Y family.,similarity:Contains 1 BRCT domain.,similarity:Contains 1 umuC domain.,subunit:Monomer. Binds MAD2L2, POLH, POLI, POLK and REV3L. May bind ITGA3.,tissue specificity:Ubiquitous.,
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