功能: domain:The C-terminus may interact with HDAC-dependent and HDAC-independent corepressors.,domain:The N-terminus may interact with a transcriptional coactivator.,function:Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.,PTM:Acetylated.,similarity:Belongs to the SAP130 family.,subunit:Component of a mSin3A corepressor complex that contains SIN3A, SAP130, SUDS3/SAP45, ARID4B/SAP180, HDAC1 and HDAC2.,tissue specificity:Expressed in various cancer cell ines.,
功能: domain:The C-terminus may interact with HDAC-dependent and HDAC-independent corepressors.,domain:The N-terminus may interact with a transcriptional coactivator.,function:Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes.,PTM:Acetylated.,similarity:Belongs to the SAP130 family.,subunit:Component of a mSin3A corepressor complex that contains SIN3A, SAP130, SUDS3/SAP45, ARID4B/SAP180, HDAC1 and HDAC2.,tissue specificity:Expressed in various cancer cell ines.,