功能： domain:The Ig-like V-type domain 2 mediates interaction with CXADR.,function:May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.,induction:Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,subcellular location:Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.,subunit:Interacts with CXADR.,tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Single-pass type I membrane protein . Cell junction . Localized at the plasma membrane and enriched in areas of cell-cell contacts (PubMed:12869515).
组织表达： Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus. Preferentially expressed by mature leukocytes (at protein level).
科研货号： PLA007620
JAML1 Polyclonal Antibody
Catalog NoPLA007620
Product information
基因名称： AMICA1 JAML UNQ722/PRO1387
蛋白名称： Junctional adhesion molecule-like (Adhesion molecule interacting with CXADR antigen 1) (Dendritic cell-specific protein CREA7-1)
功能： domain:The Ig-like V-type domain 2 mediates interaction with CXADR.,function:May function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.,induction:Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,subcellular location:Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.,subunit:Interacts with CXADR.,tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Single-pass type I membrane protein . Cell junction . Localized at the plasma membrane and enriched in areas of cell-cell contacts (PubMed:12869515).
组织表达： Expression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus. Preferentially expressed by mature leukocytes (at protein level).
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