功能： domain:PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4.,function:May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.,similarity:Belongs to the GRIP2 family.,similarity:Contains 7 PDZ (DHR) domains.,subunit:Interacts with EFNB1, EFNB3, GRIA2, GRIA3, CSPG4 and GRIPAP1. Can form homomultimers and heteromultimers with GRIP1 (By similarity). Interacts with the C-terminal tail of PRLHR.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Membrane ; Peripheral membrane protein .
组织表达： Brain,Spleen,
科研货号： PLA007592
GRIP2 Polyclonal Antibody
Catalog NoPLA007592
Product information
基因名称： GRIP2 KIAA1719
蛋白名称： Glutamate receptor-interacting protein 2 (GRIP-2)
功能： domain:PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4.,function:May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.,similarity:Belongs to the GRIP2 family.,similarity:Contains 7 PDZ (DHR) domains.,subunit:Interacts with EFNB1, EFNB3, GRIA2, GRIA3, CSPG4 and GRIPAP1. Can form homomultimers and heteromultimers with GRIP1 (By similarity). Interacts with the C-terminal tail of PRLHR.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Membrane ; Peripheral membrane protein .
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