信号通路: MAPK_ERK_Growth;MAPK_G_Protein;Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;T_Cell_Receptor;Intestinal immune network for IgA production;Epithelial cell signaling in Helicobacter pylori infection;
功能: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Induces the processing of NF-kappa-B 2/P100. Could act in a receptor-selective manner.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds to TRAF2, TRAF5, TRAF6, IKKA and NF-kappa-B 2/P100 (By similarity). Interacts with PELI3. Interacts with NIBP; the interaction is direct.,tissue specificity:Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm.
组织表达: Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon.
信号通路: MAPK_ERK_Growth;MAPK_G_Protein;Apoptosis_Inhibition;Apoptosis_Mitochondrial;Apoptosis_Overview;T_Cell_Receptor;Intestinal immune network for IgA production;Epithelial cell signaling in Helicobacter pylori infection;
功能: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity. Induces the processing of NF-kappa-B 2/P100. Could act in a receptor-selective manner.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds to TRAF2, TRAF5, TRAF6, IKKA and NF-kappa-B 2/P100 (By similarity). Interacts with PELI3. Interacts with NIBP; the interaction is direct.,tissue specificity:Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm.
组织表达: Weakly expressed in testis, small intestine, spleen, thymus, peripheral blood leukocytes, prostate, ovary and colon.