功能: function:Sequence-specific DNA-binding protein with transcriptional repression activity. Binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core. May play a role in the organization of chromosomes in the nucleus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 4 C2H2-type zinc fingers.,subcellular location:Associates with condensed chromatin.,subunit:Interacts with DNMT3A.,tissue specificity:Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus. Associates with condensed chromatin.
组织表达: Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.
科研货号: PLA007390
ZN238 Polyclonal Antibody
Catalog NoPLA007390
Product information
基因名称: ZNF238 RP58 TAZ1 ZBTB18
蛋白名称: Zinc finger protein 238 (58 kDa repressor protein) (Transcriptional repressor RP58) (Translin-associated zinc finger protein 1) (TAZ-1) (Zinc finger and BTB domain-containing protein 18) (Zinc finger protein C2H2-171)
功能: function:Sequence-specific DNA-binding protein with transcriptional repression activity. Binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core. May play a role in the organization of chromosomes in the nucleus.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 4 C2H2-type zinc fingers.,subcellular location:Associates with condensed chromatin.,subunit:Interacts with DNMT3A.,tissue specificity:Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus. Associates with condensed chromatin.
组织表达: Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.