功能： alternative products:Additional isoforms seem to exist,function:SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death.,miscellaneous:Silencing of BNIP1 disrupts ER morphology.,similarity:Belongs to the SEC20 family.,subunit:Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18, RINT1/TIP20L and NAPA. Interacts with ZW10 through RINT1. Interacts with BCL2 and adenovirus E1B 19 kDa protein.,tissue specificity:High levels of isoform 1 in heart, brain, liver skeletal muscle and pancreas. Moderate levels of isoform 3 in placenta, lung and kidney. High levels of isoform 4 in testis and small intestine.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Single-pass type IV membrane protein . Mitochondrion membrane ; Single-pass type IV membrane protein . Localization to the mitochondrion is regulated by RNF186. .
组织表达： Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine.
科研货号： PLA007370
SEC20 Polyclonal Antibody
Catalog NoPLA007370
Product information
基因名称： BNIP1 NIP1 SEC20L TRG8
蛋白名称： Vesicle transport protein SEC20 (BCL2/adenovirus E1B 19 kDa protein-interacting protein 1) (Transformation-related gene 8 protein) (TRG-8)
功能： alternative products:Additional isoforms seem to exist,function:SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death.,miscellaneous:Silencing of BNIP1 disrupts ER morphology.,similarity:Belongs to the SEC20 family.,subunit:Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18, RINT1/TIP20L and NAPA. Interacts with ZW10 through RINT1. Interacts with BCL2 and adenovirus E1B 19 kDa protein.,tissue specificity:High levels of isoform 1 in heart, brain, liver skeletal muscle and pancreas. Moderate levels of isoform 3 in placenta, lung and kidney. High levels of isoform 4 in testis and small intestine.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Single-pass type IV membrane protein . Mitochondrion membrane ; Single-pass type IV membrane protein . Localization to the mitochondrion is regulated by RNF186. .
组织表达： Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine.
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