功能： catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,subcellular location:Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.,subunit:The ubiquitin-loaded form interacts specifically with importin-11 (IPO11), leading to its import into the nucleus (By similarity). Interacts with NEDD4L.,tissue specificity:Ubiquitously expressed at low levels. Highly expressed in skeletal muscle.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.
组织表达： Ubiquitously expressed at low levels. Highly expressed in skeletal muscle.
功能： catalytic activity:ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.,function:Catalyzes the covalent attachment of ubiquitin to other proteins. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-conjugating enzyme family.,subcellular location:Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.,subunit:The ubiquitin-loaded form interacts specifically with importin-11 (IPO11), leading to its import into the nucleus (By similarity). Interacts with NEDD4L.,tissue specificity:Ubiquitously expressed at low levels. Highly expressed in skeletal muscle.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Shuttles between the nucleus and cytoplasm in a IPO11-dependent manner.
组织表达： Ubiquitously expressed at low levels. Highly expressed in skeletal muscle.
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