功能： alternative products:Named isoforms=3,function:Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-activating E1 family.,tissue specificity:Widely expressed. Isoform 2 is predominantly expressed in testis with higher expression in adult testis than in fetal testis.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： cytoplasm,cytosol,integral component of membrane,
组织表达： Widely expressed. Isoform 2 is predominantly expressed in testis with higher expression in adult testis than in fetal testis.
科研货号： PLA007332
UBA6 Polyclonal Antibody
Catalog NoPLA007332
Product information
基因名称： UBA6 MOP4 UBE1L2
蛋白名称： Ubiquitin-like modifier-activating enzyme 6 (Ubiquitin-activating enzyme 6) (Monocyte protein 4) (MOP-4) (Ubiquitin-activating enzyme E1-like protein 2) (E1-L2)
功能： alternative products:Named isoforms=3,function:Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the ubiquitin-activating E1 family.,tissue specificity:Widely expressed. Isoform 2 is predominantly expressed in testis with higher expression in adult testis than in fetal testis.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： cytoplasm,cytosol,integral component of membrane,
组织表达： Widely expressed. Isoform 2 is predominantly expressed in testis with higher expression in adult testis than in fetal testis.
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