功能： function:Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.,PTM:Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TOM1 family.,similarity:Contains 1 GAT domain.,similarity:Contains 1 VHS domain.,subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Golgi apparatus, Golgi stack. Endosome membrane . Cytoplasm . Membrane ; Peripheral membrane protein ; Cytoplasmic side . A small proportion is membrane-associated. .
组织表达： Kidney,Trachea,
科研货号： PLA007265
TM1L1 Polyclonal Antibody
Catalog NoPLA007265
Product information
基因名称： TOM1L1 SRCASM
蛋白名称： TOM1-like protein 1 (Src-activating and signaling molecule protein) (Target of Myb-like protein 1)
功能： function:Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.,PTM:Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TOM1 family.,similarity:Contains 1 GAT domain.,similarity:Contains 1 VHS domain.,subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Golgi apparatus, Golgi stack. Endosome membrane . Cytoplasm . Membrane ; Peripheral membrane protein ; Cytoplasmic side . A small proportion is membrane-associated. .
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