功能: function:Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.,similarity:Belongs to the potassium channel KCNN family.,subunit:Heterooligomer. The complex is composed of 4 channel subunits each of which binds to a calmodulin subunit which regulates the channel activity through calcium-binding.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Membrane; Multi-pass membrane protein.
组织表达: Fetal brain,Hippocampus,
科研货号: PLA007167
KCNN1 Polyclonal Antibody
Catalog NoPLA007167
Product information
基因名称: KCNN1 SK
蛋白名称: Small conductance calcium-activated potassium channel protein 1 (SK1) (SKCa 1) (SKCa1) (KCa2.1)
功能: function:Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.,similarity:Belongs to the potassium channel KCNN family.,subunit:Heterooligomer. The complex is composed of 4 channel subunits each of which binds to a calmodulin subunit which regulates the channel activity through calcium-binding.,