蛋白名称: Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53) (PP1-binding protein of 114 kDa) (Phosphatase 1 nuclear targeting subunit) (Protein FB19) (p99)
功能: function:Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.,PTM:Phosphorylated on Ser-398 and Thr-400 by PKA within the region necessary for interaction with PPP1CA.,similarity:Contains 1 C3H1-type zinc finger.,similarity:Contains 1 TFIIS N-terminal domain.,subcellular location:Found in discrete nucleoplasmic bodies and within nucleoli.,subunit:Interacts with PPP1CA and PPP1CC.,tissue specificity:Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus . Found in discrete nucleoplasmic bodies and within nucleoli. Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase (By similarity). .
组织表达: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
科研货号: PLA007127
PP1RA Polyclonal Antibody
Catalog NoPLA007127
Product information
基因名称: PPP1R10 CAT53 FB19 PNUTS
蛋白名称: Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53) (PP1-binding protein of 114 kDa) (Phosphatase 1 nuclear targeting subunit) (Protein FB19) (p99)
功能: function:Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.,PTM:Phosphorylated on Ser-398 and Thr-400 by PKA within the region necessary for interaction with PPP1CA.,similarity:Contains 1 C3H1-type zinc finger.,similarity:Contains 1 TFIIS N-terminal domain.,subcellular location:Found in discrete nucleoplasmic bodies and within nucleoli.,subunit:Interacts with PPP1CA and PPP1CC.,tissue specificity:Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus . Found in discrete nucleoplasmic bodies and within nucleoli. Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase (By similarity). .
组织表达: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.