功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Interaction with Golgi matrix protein GOLGA2 leads to autophosphorylation on Thr-174, possibly as a consequence of stabilization of dimer formation. The C-terminal non-catalytic region inhibits the kinase activity.,function:Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Localizes to the Golgi apparatus.,subunit:Homodimer.,tissue specificity:Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Golgi apparatus . Localizes to the Golgi apparatus.
组织表达： Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung.
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Interaction with Golgi matrix protein GOLGA2 leads to autophosphorylation on Thr-174, possibly as a consequence of stabilization of dimer formation. The C-terminal non-catalytic region inhibits the kinase activity.,function:Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Localizes to the Golgi apparatus.,subunit:Homodimer.,tissue specificity:Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Golgi apparatus . Localizes to the Golgi apparatus.
组织表达： Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung.
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