功能： caution:The translocation involving this gene was originally published as t(X;11)(q13;23) (PubMed:15543602), but BRWD3 is localized to Xq21 and not to Xq13.,developmental stage:Low expression is found in fetal liver.,disease:A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes.,function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed predominantly in the brain. Lower expression is found in lymph nodes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： cytosol,
组织表达： Expressed predominantly in the brain. Lower expression is found in lymph nodes.
科研货号： PLA007066
RHG20 Polyclonal Antibody
Catalog NoPLA007066
Product information
基因名称： ARHGAP20 KIAA1391
蛋白名称： Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20)
功能： caution:The translocation involving this gene was originally published as t(X;11)(q13;23) (PubMed:15543602), but BRWD3 is localized to Xq21 and not to Xq13.,developmental stage:Low expression is found in fetal liver.,disease:A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes.,function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed predominantly in the brain. Lower expression is found in lymph nodes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： cytosol,
组织表达： Expressed predominantly in the brain. Lower expression is found in lymph nodes.
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