功能： developmental stage:Preferentially expressed in normal human mammary epithelial cells as opposed to tumor-derived ones. The level of S100L was shown to correlate inversely with tumor progression.,function:May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also play a role in suppressing tumor cell growth.,induction:By growth factors in early G1 phase and probably by cell-cycle regulation in S phase. DNA methylation probably plays a direct negative role in suppressing S100L gene expression in tumor cells.,miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,tissue specificity:A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
组织表达： A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes.
科研货号： PLA006973
S10A2 Polyclonal Antibody
Catalog NoPLA006973
Product information
基因名称： S100A2 S100L
蛋白名称： Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
功能： developmental stage:Preferentially expressed in normal human mammary epithelial cells as opposed to tumor-derived ones. The level of S100L was shown to correlate inversely with tumor progression.,function:May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also play a role in suppressing tumor cell growth.,induction:By growth factors in early G1 phase and probably by cell-cycle regulation in S phase. DNA methylation probably plays a direct negative role in suppressing S100L gene expression in tumor cells.,miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,tissue specificity:A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
组织表达： A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes.
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