蛋白名称： Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
功能： domain:The WW domains are essential for localization to nuclear speckles.,function:Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). May be involved in pre-mRNA splicing.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 409.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the PRPF40 family.,similarity:Contains 2 WW domains.,similarity:Contains 5 FF domains.,subunit:Interacts with the N-terminus of HTT. Interacts with the phosphorylated carboxyterminal domain of POLR2A. Interacts with SF1, SRPK1 CARD8, ATBF1 and MECP2 (By similarity). Interacts through the WW domains with formin proline-rich regions and with WASL/N-WASP.,tissue specificity:Widely expressed.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus speckle . Nucleus matrix . Colocalizes with AKAP8L in the nuclear matrix. .
组织表达： Expressed in the brain cortex (at protein level). Widely expressed.
蛋白名称： Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)
功能： domain:The WW domains are essential for localization to nuclear speckles.,function:Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). May be involved in pre-mRNA splicing.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 409.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the PRPF40 family.,similarity:Contains 2 WW domains.,similarity:Contains 5 FF domains.,subunit:Interacts with the N-terminus of HTT. Interacts with the phosphorylated carboxyterminal domain of POLR2A. Interacts with SF1, SRPK1 CARD8, ATBF1 and MECP2 (By similarity). Interacts through the WW domains with formin proline-rich regions and with WASL/N-WASP.,tissue specificity:Widely expressed.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus speckle . Nucleus matrix . Colocalizes with AKAP8L in the nuclear matrix. .
组织表达： Expressed in the brain cortex (at protein level). Widely expressed.
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