功能: function:Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.,similarity:Belongs to the plexin family.,similarity:Contains 1 Sema domain.,similarity:Contains 4 IPT/TIG domains.,subunit:Interacts directly with NRP1 and NRP2.,tissue specificity:Detected in fetal brain.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type I membrane protein .
功能: function:Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.,similarity:Belongs to the plexin family.,similarity:Contains 1 Sema domain.,similarity:Contains 4 IPT/TIG domains.,subunit:Interacts directly with NRP1 and NRP2.,tissue specificity:Detected in fetal brain.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type I membrane protein .