功能： disease:Defects in NR0B2 may be associated with early-onset obesity [MIM:601665].,function:Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts.,similarity:Belongs to the nuclear hormone receptor family. NR0 subfamily.,subunit:Interacts with RARA, RXRA, THRB, NR5A1, NR5A2, NR1I3, PPARA, PPARG and EID1. May also interact with HNF4A.,tissue specificity:Liver. Low levels of expression were detected in heart and pancreas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Colocalizes with NEUROD1 in the nucleus.
组织表达： Liver. Low levels of expression were detected in heart and pancreas.
tag： hot
科研货号： PLA006856
NR0B2 Polyclonal Antibody
Catalog NoPLA006856
Product information
基因名称： NR0B2 SHP
蛋白名称： Nuclear receptor subfamily 0 group B member 2 (Orphan nuclear receptor SHP) (Small heterodimer partner)
功能： disease:Defects in NR0B2 may be associated with early-onset obesity [MIM:601665].,function:Acts as a negative regulator of receptor-dependent signaling pathways. Specifically inhibits transactivation of the nuclear receptor with whom it interacts.,similarity:Belongs to the nuclear hormone receptor family. NR0 subfamily.,subunit:Interacts with RARA, RXRA, THRB, NR5A1, NR5A2, NR1I3, PPARA, PPARG and EID1. May also interact with HNF4A.,tissue specificity:Liver. Low levels of expression were detected in heart and pancreas.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Colocalizes with NEUROD1 in the nucleus.
组织表达： Liver. Low levels of expression were detected in heart and pancreas.
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