功能： function:Essential component of nuclear pore complex. Required for the assembly of peripheral proteins into the nuclear pore complex.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the nucleoporin Nup84/Nup107 family.,subcellular location:Located on both the cytoplasmic and nuclear sides of the nuclear pore. During mitosis, localizes to the kinetochores.,subunit:Forms part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus membrane . Nucleus, nuclear pore complex . Chromosome, centromere, kinetochore . Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755). .
组织表达： Ubiquitously expressed in fetal and adult tissues.
功能： function:Essential component of nuclear pore complex. Required for the assembly of peripheral proteins into the nuclear pore complex.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the nucleoporin Nup84/Nup107 family.,subcellular location:Located on both the cytoplasmic and nuclear sides of the nuclear pore. During mitosis, localizes to the kinetochores.,subunit:Forms part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus membrane . Nucleus, nuclear pore complex . Chromosome, centromere, kinetochore . Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755). .
组织表达： Ubiquitously expressed in fetal and adult tissues.
在线咨询
湘公网安备