功能： domain:The U-box-like region is a truncated U-box domain. It is unknown whether it is functional or not.,function:Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the NOSIP family.,subcellular location:Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle.,subunit:Interacts with NOS1 and NOS3.,tissue specificity:Expressed in heart, brain and lung. Present in endothelial cells (at protein level).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Nucleus . Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle (PubMed:16135813).
组织表达： Expressed in heart, brain and lung. Present in endothelial cells (at protein level).
科研货号： PLA006840
NOSIP Polyclonal Antibody
Catalog NoPLA006840
Product information
基因名称： NOSIP CGI-25
蛋白名称： Nitric oxide synthase-interacting protein (eNOS-interacting protein)
功能： domain:The U-box-like region is a truncated U-box domain. It is unknown whether it is functional or not.,function:Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the NOSIP family.,subcellular location:Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle.,subunit:Interacts with NOS1 and NOS3.,tissue specificity:Expressed in heart, brain and lung. Present in endothelial cells (at protein level).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Nucleus . Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle (PubMed:16135813).
组织表达： Expressed in heart, brain and lung. Present in endothelial cells (at protein level).
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