功能: function:Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses.,similarity:Belongs to the type-B carboxylesterase/lipase family.,subcellular location:Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities.,subunit:Interacts with neurexin 1-beta, neurexin 2-beta and neurexin 3-beta. Interacts through its C-terminus with DLG4/PSD-95 third PDZ domain. Interacts with AIP1 and PDZRN3.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, postsynaptic density . Cell junction, synapse, synaptic cleft . Cell junction, synapse, synaptic cell membrane . Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. Colocalized with DLG4/PSD-95 and GRIN1/NMDAR1. .
组织表达: Expressed in the blood vessel walls (at protein level). Highly expressed in brain through prenatal stages, and at lower levels in pancreas islet beta cells.
功能: function:Neuronal cell surface protein thought to be involved in cell-cell-interactions by forming intercellular junctions through binding to beta-neurexins. Seems to play role in formation or maintenance of synaptic junctions. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses.,similarity:Belongs to the type-B carboxylesterase/lipase family.,subcellular location:Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities.,subunit:Interacts with neurexin 1-beta, neurexin 2-beta and neurexin 3-beta. Interacts through its C-terminus with DLG4/PSD-95 third PDZ domain. Interacts with AIP1 and PDZRN3.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, postsynaptic density . Cell junction, synapse, synaptic cleft . Cell junction, synapse, synaptic cell membrane . Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. Colocalized with DLG4/PSD-95 and GRIN1/NMDAR1. .
组织表达: Expressed in the blood vessel walls (at protein level). Highly expressed in brain through prenatal stages, and at lower levels in pancreas islet beta cells.