功能： developmental stage:Reaches an expression peak in the third day after induction and remains at similar level during successive myotubule maturation.,disease:Defects in MYO18B are associated with lung cancer. Inactivated in half of the primary lung cancers and cell lines; the causes include deletions, mutations and promoter methylation.,function:May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play an important role as a tumor suppressor in the development of lung cancer.,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,subcellular location:Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.,subunit:Homodimer. May interact with F actin through the GPA motif (Gly/Pro/Ala-rich).,tissue specificity:Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.
组织表达： Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.
功能： developmental stage:Reaches an expression peak in the third day after induction and remains at similar level during successive myotubule maturation.,disease:Defects in MYO18B are associated with lung cancer. Inactivated in half of the primary lung cancers and cell lines; the causes include deletions, mutations and promoter methylation.,function:May be involved in intracellular trafficking of the muscle cell when in the cytoplasm, whereas entering the nucleus, may be involved in the regulation of muscle specific genes. May play an important role as a tumor suppressor in the development of lung cancer.,similarity:Contains 1 IQ domain.,similarity:Contains 1 myosin head-like domain.,subcellular location:Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.,subunit:Homodimer. May interact with F actin through the GPA motif (Gly/Pro/Ala-rich).,tissue specificity:Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm. Nucleus. Cytoplasm, myofibril, sarcomere. Punctate pattern in undifferentiated myoblasts. Nuclear, on primary cardiomyocytes and adult muscle. A partial sarcomeric location was found in some cardiomyocytes.
组织表达： Selectively expressed in cardiac and skeletal muscles. Weakly expressed in testis, pancreas, placenta, prostate, lung and thymus.
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