功能： domain:Has a highly basic region with many copies of the sequence KKEE and KKEI/V, repeated but not at fixed intervals, which is responsible for the binding of MAP1B to microtubules.,function:The function of brain MAPS is essentially unknown. Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules.,PTM:LC1 is generated from MAP1B by proteolytic processing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MAP1 family.,subunit:3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. LC1 interacts with the amino-terminal region of MAP1B. Interacts with ANP32A and TIAM2 (By similarity). Interacts (via C-terminus) with GAN (via Kelch domains).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton . Cytoplasm . Cell junction, synapse . Cell projection, dendritic spine . Colocalizes with DAPK1 in the microtubules and cortical actin fibers. .; [MAP1 light chain LC1]: Cytoplasm .
功能： domain:Has a highly basic region with many copies of the sequence KKEE and KKEI/V, repeated but not at fixed intervals, which is responsible for the binding of MAP1B to microtubules.,function:The function of brain MAPS is essentially unknown. Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B Binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules.,PTM:LC1 is generated from MAP1B by proteolytic processing.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MAP1 family.,subunit:3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. LC1 interacts with the amino-terminal region of MAP1B. Interacts with ANP32A and TIAM2 (By similarity). Interacts (via C-terminus) with GAN (via Kelch domains).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton . Cytoplasm . Cell junction, synapse . Cell projection, dendritic spine . Colocalizes with DAPK1 in the microtubules and cortical actin fibers. .; [MAP1 light chain LC1]: Cytoplasm .
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