信号通路: Synthesis and degradation of ketone bodies;Valine; leucine and isoleucine degradation;Butanoate metabolism;Terpenoid backbone biosynthesis;
功能: catalytic activity:Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.,function:This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.,pathway:Metabolic intermediate biosynthesis; mevalonic acid biosynthesis; (R)-mevalonic acid from acetyl-CoA: step 2/3.,similarity:Belongs to the HMG-CoA synthase family.,
信号通路: Synthesis and degradation of ketone bodies;Valine; leucine and isoleucine degradation;Butanoate metabolism;Terpenoid backbone biosynthesis;
功能: catalytic activity:Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.,function:This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.,pathway:Metabolic intermediate biosynthesis; mevalonic acid biosynthesis; (R)-mevalonic acid from acetyl-CoA: step 2/3.,similarity:Belongs to the HMG-CoA synthase family.,