功能： function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity.,similarity:Belongs to the glycosyl hydrolase 47 family.,subunit:Interacts with DERL2 and DERL3.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
组织表达： Bone marrow,Primary B-Cells,Skin,
科研货号： PLA006559
EDEM1 Polyclonal Antibody
Catalog NoPLA006559
Product information
基因名称： EDEM1 EDEM KIAA0212
蛋白名称： ER degradation-enhancing alpha-mannosidase-like 1
功能： function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity.,similarity:Belongs to the glycosyl hydrolase 47 family.,subunit:Interacts with DERL2 and DERL3.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
在线咨询
湘公网安备