信号通路： Purine metabolism;Pyrimidine metabolism;Nicotinate and nicotinamide metabolism;
功能： catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Binds 1 magnesium ion per subunit.,disease:Aberration of this enzyme may be related to the urate production in hyperuricemia and gout.,enzyme regulation:Allosterically activated by various compounds, including ATP.,function:May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.,similarity:Belongs to the 5'(3')-deoxyribonucleotidase family.,subunit:Homotetramer.,
信号通路： Purine metabolism;Pyrimidine metabolism;Nicotinate and nicotinamide metabolism;
功能： catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Binds 1 magnesium ion per subunit.,disease:Aberration of this enzyme may be related to the urate production in hyperuricemia and gout.,enzyme regulation:Allosterically activated by various compounds, including ATP.,function:May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.,similarity:Belongs to the 5'(3')-deoxyribonucleotidase family.,subunit:Homotetramer.,
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