功能: function:Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA.,similarity:Belongs to the sulfotransferase 2 family.,tissue specificity:Widely expressed. Expressed at high level in pituitary gland, placenta, uterus and thyroid.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Golgi apparatus membrane ; Single-pass type II membrane protein .
组织表达: Widely expressed. Expressed at high level in pituitary gland, placenta, uterus and thyroid.
功能: function:Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA.,similarity:Belongs to the sulfotransferase 2 family.,tissue specificity:Widely expressed. Expressed at high level in pituitary gland, placenta, uterus and thyroid.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Golgi apparatus membrane ; Single-pass type II membrane protein .
组织表达: Widely expressed. Expressed at high level in pituitary gland, placenta, uterus and thyroid.