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ENOB Polyclonal Antibody
商品货号: PLA006364
适 应 性: 人,小鼠,大鼠
WB ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: ENO3
  • 蛋白名称: Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase)
  • Human_gene_id: 2027
  • Human_swiss_prot_no: P13929
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P13929/entry
  • Mouse_swiss_prot_no: P21550
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P21550
  • Rat_swiss_prot_no: P15429
  • Rat_swiss_link: http://www.uniprot.org/uniprot/O54941P15429
  • 特异性: ENOB Polyclonal Antibody detects endogenous levels of protein.
  • 组成: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000 ELISA 1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 实测条带: 47kD
  • 信号通路: Glycolysis / Gluconeogenesis;RNA degradation;
  • 功能: catalytic activity:2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O.,cofactor:Magnesium. Required for catalysis and for stabilizing the dimer.,developmental stage:During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.,disease:Defects in ENO3 are the cause of muscle-specific enolase-beta deficiency (glycogenesis type XIII) [MIM:131370]. It is a glycogen storage myopathy which results in exercise-induced myalgias, generalized muscle weakness and fatigability. Dramatically reduced protein levels with focal sarcoplasmic accumulation of glycogen-beta particles are detected in patients.,function:Appears to have a function in striated muscle development and regeneration.,pathway:Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.,similarity:Belongs to the enolase family.,subcellular location:Localized to the Z line. Some colocalization with CKM at M-band.,subunit:Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. Interacts with PNKD.,tissue specificity:The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm. Localized to the Z line. Some colocalization with CKM at M-band (By similarity). .
  • 组织表达: The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
  • 科研货号: PLA006364
ENOB Polyclonal Antibody
Catalog No PLA006364
Product information
  • 基因名称: ENO3
  • 蛋白名称: Beta-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Enolase 3) (Muscle-specific enolase) (MSE) (Skeletal muscle enolase)
  • Human_gene_id: 2027
  • Human_swiss_prot_no: P13929
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P13929/entry
  • Mouse_swiss_prot_no: P21550
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P21550
  • Rat_swiss_prot_no: P15429
  • Rat_swiss_link: http://www.uniprot.org/uniprot/O54941P15429
  • 特异性: ENOB Polyclonal Antibody detects endogenous levels of protein.
  • 组成: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000 ELISA 1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 实测条带: 47kD
  • 信号通路: Glycolysis / Gluconeogenesis;RNA degradation;
  • 功能: catalytic activity:2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O.,cofactor:Magnesium. Required for catalysis and for stabilizing the dimer.,developmental stage:During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells.,disease:Defects in ENO3 are the cause of muscle-specific enolase-beta deficiency (glycogenesis type XIII) [MIM:131370]. It is a glycogen storage myopathy which results in exercise-induced myalgias, generalized muscle weakness and fatigability. Dramatically reduced protein levels with focal sarcoplasmic accumulation of glycogen-beta particles are detected in patients.,function:Appears to have a function in striated muscle development and regeneration.,pathway:Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.,similarity:Belongs to the enolase family.,subcellular location:Localized to the Z line. Some colocalization with CKM at M-band.,subunit:Mammalian enolase is composed of 3 isozyme subunits, alpha, beta and gamma, which can form homodimers or heterodimers which are cell-type and development-specific. Interacts with PNKD.,tissue specificity:The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm. Localized to the Z line. Some colocalization with CKM at M-band (By similarity). .
  • 组织表达: The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
  • 科研货号: PLA006364
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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