功能: domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water channel. Not permeable to urea and glycerol. May contribute to water transport in the upper portion of small intestine.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Expressed exclusively in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Apical cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Lipid droplet . Detected around lipid droplets. .
组织表达: Detected in epithelial cells on villi in the ileum, and also in stomach, jejunum, colon, rectum, white adipose tissue and placenta (at protein level) (PubMed:15221416, PubMed:23382902). Expressed in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum (PubMed:11573934, PubMed:12084581). Detected in subcutaneous adipose tissue (PubMed:23382902).
功能: domain:Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).,function:Forms a water channel. Not permeable to urea and glycerol. May contribute to water transport in the upper portion of small intestine.,similarity:Belongs to the MIP/aquaporin (TC 1.A.8) family.,tissue specificity:Expressed exclusively in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Apical cell membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Lipid droplet . Detected around lipid droplets. .
组织表达: Detected in epithelial cells on villi in the ileum, and also in stomach, jejunum, colon, rectum, white adipose tissue and placenta (at protein level) (PubMed:15221416, PubMed:23382902). Expressed in duodenum and jejunum. Highest expression in absorptive epithelial cells at the tips of villi in the jejunum (PubMed:11573934, PubMed:12084581). Detected in subcutaneous adipose tissue (PubMed:23382902).