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ANT3 Polyclonal Antibody
商品货号: PLA006310
适 应 性: 人,大鼠,小鼠,
WB ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: SERPINC1 AT3 PRO0309
  • 蛋白名称: Antithrombin-III (ATIII) (Serpin C1)
  • Human_gene_id: 462
  • Human_swiss_prot_no: P01008
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P01008/entry
  • Mouse_swiss_prot_no: P32261
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P32261
  • 特异性: ANT3 Polyclonal Antibody detects endogenous levels of protein.
  • 组成: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000 ELISA 1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 实测条带: 51kD
  • 信号通路: Complement and coagulation cascades;
  • 功能: disease:Defects in SERPINC1 are the cause of antithrombin-III deficiency (AT3D) [MIM:107300]. AT3D is an important risk factor for hereditary thrombophilia, a hemostatic disorder characterized by a tendency to recurrent thrombosis. AT3D is classified into 4 types. Type I: characterized by a 50% decrease in antigenic and functional levels. Type II: has defects affecting the thrombin-binding domain. Type III: alteration of the heparin-binding domain. Plasma AT-III antigen levels are normal in type II and III. Type IV: consists of miscellaneous group of unclassifiable mutations.,function:Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.,mass spectrometry: PubMed:7734359,mass spectrometry:Variant Thr-414 PubMed:7734359,online information:Antithrombin entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the serpin family.,tissue specificity:Found in plasma.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Secreted, extracellular space.
  • 组织表达: Found in plasma.
  • 科研货号: PLA006310
ANT3 Polyclonal Antibody
Catalog No PLA006310
Product information
  • 基因名称: SERPINC1 AT3 PRO0309
  • 蛋白名称: Antithrombin-III (ATIII) (Serpin C1)
  • Human_gene_id: 462
  • Human_swiss_prot_no: P01008
  • Human_swiss_link: https://www.uniprot.org/uniprotkb/P01008/entry
  • Mouse_swiss_prot_no: P32261
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P32261
  • 特异性: ANT3 Polyclonal Antibody detects endogenous levels of protein.
  • 组成: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000 ELISA 1:5000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 实测条带: 51kD
  • 信号通路: Complement and coagulation cascades;
  • 功能: disease:Defects in SERPINC1 are the cause of antithrombin-III deficiency (AT3D) [MIM:107300]. AT3D is an important risk factor for hereditary thrombophilia, a hemostatic disorder characterized by a tendency to recurrent thrombosis. AT3D is classified into 4 types. Type I: characterized by a 50% decrease in antigenic and functional levels. Type II: has defects affecting the thrombin-binding domain. Type III: alteration of the heparin-binding domain. Plasma AT-III antigen levels are normal in type II and III. Type IV: consists of miscellaneous group of unclassifiable mutations.,function:Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.,mass spectrometry: PubMed:7734359,mass spectrometry:Variant Thr-414 PubMed:7734359,online information:Antithrombin entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the serpin family.,tissue specificity:Found in plasma.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Secreted, extracellular space.
  • 组织表达: Found in plasma.
  • 科研货号: PLA006310
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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