信号通路： Glycolysis / Gluconeogenesis;Fatty acid metabolism;Tyrosine metabolism;Methane metabolism;Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Drug metabolism;
功能： catalytic activity:An alcohol + NAD(+) = an aldehyde or ketone + NADH.,catalytic activity:S-(hydroxymethyl)glutathione + NAD(P)(+) = S-formylglutathione + NAD(P)H.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Zinc.,function:Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.,miscellaneous:There are 7 different ADH's isozymes in human: three belongs to class-I: alpha, beta, and gamma, one to class-II: pi, one to class-III: chi, one to class-IV: ADH7 and one to class-V: ADH6.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.,subunit:Homodimer.,
信号通路： Glycolysis / Gluconeogenesis;Fatty acid metabolism;Tyrosine metabolism;Methane metabolism;Retinol metabolism;Metabolism of xenobiotics by cytochrome P450;Drug metabolism;
功能： catalytic activity:An alcohol + NAD(+) = an aldehyde or ketone + NADH.,catalytic activity:S-(hydroxymethyl)glutathione + NAD(P)(+) = S-formylglutathione + NAD(P)H.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Zinc.,function:Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione.,miscellaneous:There are 7 different ADH's isozymes in human: three belongs to class-I: alpha, beta, and gamma, one to class-II: pi, one to class-III: chi, one to class-IV: ADH7 and one to class-V: ADH6.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.,subunit:Homodimer.,
在线咨询
湘公网安备