功能： disease:Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11).,disease:Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation.,function:May play an important role in palate formation.,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 CUT DNA-binding domains.,tissue specificity:High expression in adult brain, moderate expression in fetal brain, and weak expression in adult liver, kidney, and spinal cord and in select brain regions, including amygdala, corpus callosum, caudate nucleus, and hippocampus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus matrix .
组织表达： High expression in adult brain, moderate expression in fetal brain, and weak expression in adult liver, kidney, and spinal cord and in select brain regions, including amygdala, corpus callosum, caudate nucleus, and hippocampus.
tag： hot
科研货号： PLA006188
SATB2 Polyclonal Antibody
Catalog NoPLA006188
Product information
基因名称： SATB2 KIAA1034
蛋白名称： DNA-binding protein SATB2 (Special AT-rich sequence-binding protein 2)
功能： disease:Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11).,disease:Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation.,function:May play an important role in palate formation.,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 CUT DNA-binding domains.,tissue specificity:High expression in adult brain, moderate expression in fetal brain, and weak expression in adult liver, kidney, and spinal cord and in select brain regions, including amygdala, corpus callosum, caudate nucleus, and hippocampus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus matrix .
组织表达： High expression in adult brain, moderate expression in fetal brain, and weak expression in adult liver, kidney, and spinal cord and in select brain regions, including amygdala, corpus callosum, caudate nucleus, and hippocampus.
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