功能： disease:Chromosomal aberrations involving CENPK are a cause of acute leukemias. Translocation t(5;11)(q12;q23) with MLL.,function:Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.,subcellular location:Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.,subunit:Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU.,tissue specificity:Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung ans placenta.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
组织表达： Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung and placenta.
科研货号： PLA006167
CENPK Polyclonal Antibody
Catalog NoPLA006167
Product information
基因名称： CENPK ICEN37 FKSG14
蛋白名称： Centromere protein K (CENP-K) (Interphase centromere complex protein 37) (Protein AF-5alpha) (p33)
功能： disease:Chromosomal aberrations involving CENPK are a cause of acute leukemias. Translocation t(5;11)(q12;q23) with MLL.,function:Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.,subcellular location:Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.,subunit:Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and MLF1IP/CENPU.,tissue specificity:Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung ans placenta.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
组织表达： Detected in several fetal organs with highest levels in fetal liver. In adults, it is weakly expressed in lung and placenta.
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