功能: domain:Contains a death domain involved in the binding of RIP protein.,domain:The CARD domain mediates the interaction with caspase-2.,function:Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruites caspase-2 to the TNFR-1 signalling complex.,similarity:Contains 1 CARD domain.,similarity:Contains 1 death domain.,subunit:Interacts with LRDD.,tissue specificity:Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm . Nucleus .
组织表达: Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
科研货号: PLA006157
CRADD Polyclonal Antibody
Catalog NoPLA006157
Product information
基因名称: CRADD RAIDD
蛋白名称: Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)
功能: domain:Contains a death domain involved in the binding of RIP protein.,domain:The CARD domain mediates the interaction with caspase-2.,function:Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruites caspase-2 to the TNFR-1 signalling complex.,similarity:Contains 1 CARD domain.,similarity:Contains 1 death domain.,subunit:Interacts with LRDD.,tissue specificity:Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm . Nucleus .
组织表达: Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.