CDA7L Polyclonal Antibody

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商品货号： PLA006036

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： CDCA7L HR1 JPO2 R1
蛋白名称： Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2)
Human_gene_id： 55536
Human_swiss_prot_no： Q96GN5
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q96GN5/entry
Mouse_swiss_prot_no： Q922M5
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q922M5
Rat_swiss_prot_no： Q4G059
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941Q4G059
特异性： CDA7L Polyclonal Antibody detects endogenous levels of protein.
组成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
实测条带： 49kD
功能： function:Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.,induction:By MYC overexpression in a concentration dependent manner in neuroblastoma cell line.,miscellaneous:Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell lines. CDCA7L overexpression induces colony formation.,subcellular location:Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.,subunit:Interacts with MYC and PSIP1.,tissue specificity:Ubiquitous. Overexpressed in medulloblastoma.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm. Nucleus. Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.
组织表达： Ubiquitous. Overexpressed in medulloblastoma.
科研货号： PLA006036

CDA7L Polyclonal Antibody

Catalog No PLA006036

Product information

基因名称： CDCA7L HR1 JPO2 R1
蛋白名称： Cell division cycle-associated 7-like protein (Protein JPO2) (Transcription factor RAM2)
Human_gene_id： 55536
Human_swiss_prot_no： Q96GN5
Human_swiss_link： https://www.uniprot.org/uniprotkb/Q96GN5/entry
Mouse_swiss_prot_no： Q922M5
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q922M5
Rat_swiss_prot_no： Q4G059
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941Q4G059
特异性： CDA7L Polyclonal Antibody detects endogenous levels of protein.
组成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000 ELISA 1:5000-20000
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
实测条带： 49kD
功能： function:Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.,induction:By MYC overexpression in a concentration dependent manner in neuroblastoma cell line.,miscellaneous:Cells lacking CDCA7L display a reduction of 25-30% of colony formation in medulloblastoma cell lines. CDCA7L overexpression induces colony formation.,subcellular location:Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.,subunit:Interacts with MYC and PSIP1.,tissue specificity:Ubiquitous. Overexpressed in medulloblastoma.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm. Nucleus. Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.
组织表达： Ubiquitous. Overexpressed in medulloblastoma.
科研货号： PLA006036

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