功能： domain:RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes.,similarity:Contains 2 spectrin repeats.,subcellular location:In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences.,subunit:Interacts with RII subunit of PKA, phosphatase 2B (calcineurin) and AKAP79.,tissue specificity:Highly expressed in cardiac and skeletal muscle, followed by brain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Sarcoplasmic reticulum. Nucleus membrane. In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences.
组织表达： Highly expressed in cardiac and skeletal muscle, followed by brain.
科研货号： PLA005973
AKAP6 Polyclonal Antibody
Catalog NoPLA005973
Product information
基因名称： AKAP6 AKAP100 KIAA0311
蛋白名称： A-kinase anchor protein 6 (AKAP-6) (A-kinase anchor protein 100 kDa) (AKAP 100) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP)
功能： domain:RII-alpha binding site, predicted to form an amphipathic helix, could participate in protein-protein interactions with a complementary surface on the R-subunit dimer.,function:Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes.,similarity:Contains 2 spectrin repeats.,subcellular location:In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences.,subunit:Interacts with RII subunit of PKA, phosphatase 2B (calcineurin) and AKAP79.,tissue specificity:Highly expressed in cardiac and skeletal muscle, followed by brain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Sarcoplasmic reticulum. Nucleus membrane. In heart muscle. Participation of multiple targeting signals allow correct intracellular targeting. These may be repeated motifs rich in basic and hydrophobic amino acids, palmitoylated/myristoylated motifs or alternatively splice targeting sequences.
组织表达： Highly expressed in cardiac and skeletal muscle, followed by brain.
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