功能： function:May be involved in coupling the protein kinase C and calmodulin signal transduction systems.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MARCKS family.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton . Cell membrane ; Lipid-anchor . Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca(2+)/calmodulin. Colocalizes with F-actin at the leading edge of migrating cells (By similarity). In prostate cancers, shows strong expression at apical and/or basal regions of the cell and also has weak cytoplasmic expression (PubMed:22751924). .
组织表达： Brain,Epithelium,Muscle,
科研货号： PLA005960
MRP Polyclonal Antibody
Catalog NoPLA005960
Product information
基因名称： MARCKSL1 MLP MRP
蛋白名称： MARCKS-related protein (MARCKS-like protein 1) (Macrophage myristoylated alanine-rich C kinase substrate) (Mac-MARCKS) (MacMARCKS)
功能： function:May be involved in coupling the protein kinase C and calmodulin signal transduction systems.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MARCKS family.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton . Cell membrane ; Lipid-anchor . Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca(2+)/calmodulin. Colocalizes with F-actin at the leading edge of migrating cells (By similarity). In prostate cancers, shows strong expression at apical and/or basal regions of the cell and also has weak cytoplasmic expression (PubMed:22751924). .
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