功能： disease:A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(14;19)(q32;q13.1) with immunoglobulin gene regions.,function:Could be a transcriptional activating factor. Functions as a form of I-kappa-B specific for NF-kappa-B p50 subunit inhibiting its translocation to the nucleus.,PTM:Activated by phosphorylation.,similarity:Contains 7 ANK repeats.,subunit:Component of a complex consisting of the NF-kappa-B p52-p52 homodimer and BCL3. Component of a complex consisting of the NF-kappa-B p50-p50 homodimer and BCL3. Interacts with N4BP2 and COPS5.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus. Cytoplasm . Cytoplasm, perinuclear region . Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation. .
组织表达： Leukemia,Lung,
科研货号： PLA005925
BCL3 Polyclonal Antibody
Catalog NoPLA005925
Product information
基因名称： BCL3 BCL4 D19S37
蛋白名称： B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3)
功能： disease:A chromosomal aberration involving BCL3 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(14;19)(q32;q13.1) with immunoglobulin gene regions.,function:Could be a transcriptional activating factor. Functions as a form of I-kappa-B specific for NF-kappa-B p50 subunit inhibiting its translocation to the nucleus.,PTM:Activated by phosphorylation.,similarity:Contains 7 ANK repeats.,subunit:Component of a complex consisting of the NF-kappa-B p52-p52 homodimer and BCL3. Component of a complex consisting of the NF-kappa-B p50-p50 homodimer and BCL3. Interacts with N4BP2 and COPS5.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus. Cytoplasm . Cytoplasm, perinuclear region . Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation. .
在线咨询
湘公网安备