功能： function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.,PTM:Fatty acylated. Heavily palmitoylated in the cysteine string motif.,PTM:Phosphorylated, mainly on serine residues.,similarity:Contains 1 RGS domain.,subunit:Interacts with GIPC PDZ domain.,tissue specificity:Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane; Lipid-anchor.
组织表达： Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.
科研货号： PLA005907
RGS19 Polyclonal Antibody
Catalog NoPLA005907
Product information
基因名称： RGS19 GAIP GNAI3IP
蛋白名称： Regulator of G-protein signaling 19 (RGS19) (G-alpha-interacting protein) (GAIP)
功能： function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.,PTM:Fatty acylated. Heavily palmitoylated in the cysteine string motif.,PTM:Phosphorylated, mainly on serine residues.,similarity:Contains 1 RGS domain.,subunit:Interacts with GIPC PDZ domain.,tissue specificity:Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Membrane; Lipid-anchor.
组织表达： Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.
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