功能: function:Induces apoptotic chromatin condensation after activation by CASP3.,PTM:Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.,similarity:Contains 1 SAP domain.,subunit:Interacts with API5.,tissue specificity:Ubiquitous.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus. Nucleus speckle. Nucleus, nucleoplasm. Phosphorylation on Ser-1180 by SRPK2 redistributes it from the nuclear speckles to the nucleoplasm.
组织表达: Ubiquitous. The Ser-1180 phosphorylated form (by SRPK2) is highly expressed and phosphorylated in patients with myeloid hematologic malignancies.
科研货号: PLA005900
ACINU Polyclonal Antibody
Catalog NoPLA005900
Product information
基因名称: ACIN1 ACINUS KIAA0670
蛋白名称: Apoptotic chromatin condensation inducer in the nucleus (Acinus)
功能: function:Induces apoptotic chromatin condensation after activation by CASP3.,PTM:Undergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.,similarity:Contains 1 SAP domain.,subunit:Interacts with API5.,tissue specificity:Ubiquitous.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus. Nucleus speckle. Nucleus, nucleoplasm. Phosphorylation on Ser-1180 by SRPK2 redistributes it from the nuclear speckles to the nucleoplasm.
组织表达: Ubiquitous. The Ser-1180 phosphorylated form (by SRPK2) is highly expressed and phosphorylated in patients with myeloid hematologic malignancies.