Muscle actin mouse Monoclonal Antibody(3E9)

> > > >

商品货号： PLA005844

适应性： 人,大鼠,小鼠

￥600元

规格：

40μL 100μL 200μL

在线咨询

MSDS

说明书

商品描述

基因名称： ACTA1
蛋白名称： ACTA1
Human_gene_id： 58
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58
Human_swiss_prot_no： P68133
Human_swiss_link： http://www.uniprot.org/uniprotkb/P68133/entry
Mouse_swiss_prot_no： P68134
Mouse_swiss_link： http://www.uniprot.org/uniprot/P68134
Rat_swiss_prot_no： P68136
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P68136
特异性： Muscle actin protein detects endogenous levels of ACTA1
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Monoclonal, Mouse
稀释： WB 1:1000-2000, IHC 1:100-200. IF 1:50-200
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ACTA1
实测条带： 42kD
功能： disease:Defects in ACTA1 are a cause of congenital myopathy with excess of thin myofilaments (CM) [MIM:102610].,disease:Defects in ACTA1 are a cause of congenital myopathy with fiber-type disproportion (CFTD) [MIM:255310]; also known as congenital fiber-type disproportion myopathy (CFTDM). CFTD is a genetically heterogeneous disorder in which there is relative hypotrophy of type 1 muscle fibers compared to type 2 fibers on skeletal muscle biopsy. However, these findings are not specific and can be found in many different myopathic and neuropathic conditions.,disease:Defects in ACTA1 are the cause of nemaline myopathy type 3 (NEM3) [MIM:161800]. Nemaline myopathy (NEM) is a form of congenital myopathy characterized by abnormal thread- or rod-like structures in muscle fibers on histologic examination. The clinical phenotype is highly variable, with differing age at onset and severity.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the actin family.,subunit:Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Interacts with TTID.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton.
组织表达： Epithelium,Skeletal muscle,
科研货号： PLA005844

Muscle actin mouse Monoclonal Antibody(3E9)

Catalog No PLA005844

Product information

基因名称： ACTA1
蛋白名称： ACTA1
Human_gene_id： 58
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58
Human_swiss_prot_no： P68133
Human_swiss_link： http://www.uniprot.org/uniprotkb/P68133/entry
Mouse_swiss_prot_no： P68134
Mouse_swiss_link： http://www.uniprot.org/uniprot/P68134
Rat_swiss_prot_no： P68136
Rat_swiss_link： http://www.uniprot.org/uniprot/O54941P68136
特异性： Muscle actin protein detects endogenous levels of ACTA1
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Monoclonal, Mouse
稀释： WB 1:1000-2000, IHC 1:100-200. IF 1:50-200
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ACTA1
实测条带： 42kD
功能： disease:Defects in ACTA1 are a cause of congenital myopathy with excess of thin myofilaments (CM) [MIM:102610].,disease:Defects in ACTA1 are a cause of congenital myopathy with fiber-type disproportion (CFTD) [MIM:255310]; also known as congenital fiber-type disproportion myopathy (CFTDM). CFTD is a genetically heterogeneous disorder in which there is relative hypotrophy of type 1 muscle fibers compared to type 2 fibers on skeletal muscle biopsy. However, these findings are not specific and can be found in many different myopathic and neuropathic conditions.,disease:Defects in ACTA1 are the cause of nemaline myopathy type 3 (NEM3) [MIM:161800]. Nemaline myopathy (NEM) is a form of congenital myopathy characterized by abnormal thread- or rod-like structures in muscle fibers on histologic examination. The clinical phenotype is highly variable, with differing age at onset and severity.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the actin family.,subunit:Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Interacts with TTID.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton.
组织表达： Epithelium,Skeletal muscle,
科研货号： PLA005844

Hunan UPT Biotechnology Co.,Ltd

Website：www.uptbio.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.