HIF-1 β/ARNT Monoclonal Antibody(4C5)

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商品货号： PLA005815

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： ARNT
蛋白名称： Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)
Human_gene_id： 405
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=405
Human_swiss_prot_no： P27540
Human_swiss_link： http://www.uniprot.org/uniprotkb/P27540/entry
Mouse_swiss_prot_no： P53762
Mouse_swiss_link： http://www.uniprot.org/uniprot/P53762
特异性： HIF-1 β/ARNT protein detects endogenous levels of HIF-1 β/ARNT
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Monoclonal, Mouse
稀释： WB 1:1000-2000, IHC 1:100-200, IF 1:50-200
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta
实测条带： 87kD
信号通路： Pathways in cancer;Renal cell carcinoma;
功能： function:Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,similarity:Contains 1 PAC (PAS-associated C-terminal) domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with AHR, AHRR, HIF1A and EPAS1/HIF2A as well as with other bHLH proteins. Interacts with TACC3 (By similarity). Interacts with NOCA7.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus.
组织表达： Aorta endothelial cell,Brain,Kidney,Thalamus,Uterus,
科研货号： PLA005815

HIF-1 β/ARNT Monoclonal Antibody(4C5)

Catalog No PLA005815

Product information

基因名称： ARNT
蛋白名称： Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Class E basic helix-loop-helix protein 2) (bHLHe2) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1-beta) (HIF-1-beta) (HIF1-beta)
Human_gene_id： 405
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=405
Human_swiss_prot_no： P27540
Human_swiss_link： http://www.uniprot.org/uniprotkb/P27540/entry
Mouse_swiss_prot_no： P53762
Mouse_swiss_link： http://www.uniprot.org/uniprot/P53762
特异性： HIF-1 β/ARNT protein detects endogenous levels of HIF-1 β/ARNT
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Monoclonal, Mouse
稀释： WB 1:1000-2000, IHC 1:100-200, IF 1:50-200
纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ARNT; BHLHE2; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; bHLHe2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; HIF-1-beta; HIF1-beta
实测条带： 87kD
信号通路： Pathways in cancer;Renal cell carcinoma;
功能： function:Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,similarity:Contains 1 PAC (PAS-associated C-terminal) domain.,similarity:Contains 2 PAS (PER-ARNT-SIM) domains.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with AHR, AHRR, HIF1A and EPAS1/HIF2A as well as with other bHLH proteins. Interacts with TACC3 (By similarity). Interacts with NOCA7.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus.
组织表达： Aorta endothelial cell,Brain,Kidney,Thalamus,Uterus,
科研货号： PLA005815

Hunan UPT Biotechnology Co.,Ltd

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E-mail：service@uptbio.com

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